Specifying Concepts with Examples (Nature vs. Nurture)

I want to use this blog post as an opportunity to categorize what I consider to be nature or nurture.  Pinker, in his article, cites examples such as PKU (phenylketonuria, a genetic disorder in newborns) as the source for the nature vs. nurture debate.    I want to explore the social and biological constructs that might make a case for either concept. Would birth order impact either debate? Could you make a case based on comparing or contrasting personality attributes dependent on the order in which one was incorporated into a family structure? Knowing that a fertilized egg contains 46 chromosomes and each embryo differs from each other, are there any relationships biologically or familial that explain different personality traits? If a child is adopted how would the arguments change? What is your opinion about this topic?